Selected Publications

(#Co-first author; * Co-corresponding author)

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1．Xue Ruidong#, Zhang Qiming#, Cao Qi#, Kong Ruirui#, Xiang Xiao#, …, Zhu Jiye*, Zhang Zemin*, Zhang Ning*. Liver tumor immune microenvironment subtypes and neutrophil heterogeneity. Nature 2022; 612(7938): 141-147.

2．Guo Lin#, Yi Xianfu#, Chen Lu#, …, Xue Ruidong*, Zhang Ning*. Single cell DNA sequencing reveals punctuated and gradual clonal evolution in hepatocellular carcinoma. Gastroenterology 2022;162:238-252.

Editorial by Gastroenterology

3．Xiang Xiao#, Liu Ziyang#, Zhang Chong#, Li Zhao#…, Xue Ruidong*, Bai Fan*, Zhu Jiye*. IDH mutation subgroup status associates with intratumor heterogeneity and the tumor microenvironment in intrahepatic cholangiocarcinoma. Advanced Science 2021;8:e2101230.

4．Xue Ruidong#, Chen Lu#, Zhang Chong#, Fujita Masashi#, …, Zhang Zemin, Steven G Rozen, Teh Bin Tean, Wang Xin-Wei, Nakagawa Hidewaki*, Zeng Mu-Sheng*, Bai Fan*, Zhang Ning*. Genomic and transcriptomic profiling of combined hepatocellular and intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes. Cancer Cell (2019); 35: 932-947 e8. 

Editorial by Cancer Cell, News and Views by Nature Reviews G & H

5．Xue Ruidong#, Li Ruoyan#, Guo Hua#, Guo Lin#, …, Zhang Zemin, Xie Sunney Xiaoliang, Bai Fan*, Zhang Ning*. Variable intra-tumor genomic heterogeneity of multiple lesions in patients with hepatocellular carcinoma. Gastroenterology (2016); 150: 998-1008. 

Editorial by Gastroenterology

6．Zhang Chong #, Zhang Lin #, Xu Tianlei #, Xue Ruidong#, Yu Liang#, …, Bai Fan*, Zhang Haizeng*. Mapping the spreading routes of lymphatic metastases in human colorectal cancer. Nature Communications (2020); 11: 1993.

7．Li Ruoyan#, Li Xiao#, Xue Ruidong#, Yang Fan#, …, Bai Fan*, Wang Jun*. Early metastasis detected in patients with multifocal pulmonary ground-glass opacities. Thorax (2018); 73: 290-292.

8．Dong Xin, Xue Ruidong. Capture a live-photo of tumor infiltrating T cell landscape at single cell resolution. Cancer Biology & Medicine (2019); 16: 619-622.

9．Xue Ruidong# Li Jing #, …, Ji Junfang*, Lu Yinying*. A race to uncover a panoramic view of primary liver cancer. Cancer Biology & Medicine (2017); 14: 335-340.

10．Xue Ruidong, Li Ruoyan, Zhang Ning, Bai Fan. Understanding intra-tumor heterogeneity and tumor evolution to facilitate hepatocellular carcinoma therapy. Trans. Can. Res. (2016); 5: S604-S605.

11．Xue Ruidong#, Ma Qi#, Baker A. Matthew*, Bai Fan*. A Delicate Nanoscale Motor Made by Nature-The Bacterial Flagellar Motor. Advanced Science (2015); 2: 1500129.

12．Xue Ruidong, Li Ruoyan, Bai Fan. Single cell sequencing: technique, application, and future development. Science Bulletin (2015); 60: 33-42.